Cell Chemical Biology · Scour

tRNA-derived RNA promotes autophagy for kidney protection

Activation primes GPCRs for versatile coupling

Sweet signaling for ferroptosis

Structural basis of adenosine 2A receptor-balanced signaling activation relies on allosterically mediated structural dynamics

A base editor facilitates simultaneous purine and pyrimidine substitutions for ex vivo and in vivo mutagenesis screens

Pharmacologic interrogation of USP28 cellular function in p53 signaling

A covalent inhibitor targeting Cys16 on RhoA in colorectal cancer

Structural basis of adenosine 2A receptor-balanced signaling activation relies on allosterically mediated structural dynamics

A potent NLRP3 inhibitor effective against both MCC950-sensitive and -resistant inflammation

BLOC-1 and BORC: Complex regulators of endolysosomal dynamics

Disruption to the gut microbiome by non-antibiotics is linked to infection risk

tRNA-derived RNA promotes autophagy for kidney protection

Sweet signaling for ferroptosis

Activation primes GPCRs for versatile coupling

Meet the authors: Raffaella De Pace, Chad Williamson, and Juan Bonifacino

Meet the authors: Canyong Guo and Kurt Wüthrich

Robust antitumor treatment driven by lock-and-key biorecognition of dynamic cyclic diselenide-guided chiral prodrug self-assembly

Engineering affinity-matured variants of an anti-polysialic acid monoclonal antibody with superior cytotoxicity-mediating potency

Inhibiting cancer metastasis with water-solubilized membrane receptor CXCR4QTY-Fc as a molecular trap

An adjuvant database for preclinical evaluation of vaccines and immunotherapeutics

Log in to enable infinite scrolling